File:Syncell whitespace.png - Revision history

Murray: /* Summary */

2025-08-30T11:51:50Z

Summary

← Older revision		Revision as of 04:51, 30 August 2025
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	* [[Roquet2016 - Recombinase-based state machines\|Roquet FSM (2016)]]: 6-input FSM used 8 genes. Ran over 6 days [need to confirm]		* [[Roquet2016 - Recombinase-based state machines\|Roquet FSM (2016)]]: 6-input FSM used 8 genes. Ran over 6 days [need to confirm]
	* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours		* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours
			* Synthetic insulin - 2 peptides in E. coli. Batches run for 24-72 hours
	* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours		* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours
	* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours		* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours

2025-08-30T11:50:44Z

Murray uploaded a new version of File:Syncell whitespace.png

← Older revision

Revision as of 04:50, 30 August 2025

2025-08-30T11:43:18Z

Summary

← Older revision		Revision as of 04:43, 30 August 2025
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	* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours		* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours
	* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours		* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours
	* [[~~Srinivasan~~ Srinivasan and Smolke: 26 genes (+ 8 deletions) in yeast for 72 hours		* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours
	* [[http:en.wikipedia.org/wiki/Tardigrade\|Tardigrade]]: lives ~2 months, 11-14K genes		* [[http:en.wikipedia.org/wiki/Tardigrade\|Tardigrade]]: lives ~2 months, 11-14K genes
	* [[http:en.wikipedia.org/wiki/Carpenter_ant\|Carpenter ant]]: 17K genes, lives for a year, 2-6 weeks w/out food		* [[http:en.wikipedia.org/wiki/Carpenter_ant\|Carpenter ant]]: 17K genes, lives for a year, 2-6 weeks w/out food

2025-08-30T11:42:14Z

Summary

@@ Line 1: / Line 1: @@
 == Summary ==
-Initial chart.
+DARPA "white space" chart.  This chart shows a conceptual trajectory for using synthetic cells to engineering biology at scale.  The vertical axis measures the complexity of the system by the number of engineered functional elements (nominally a gene assembly, such as a repressor).  The horizontal axis measures the operational lifetime of the systems.
 == Licensing ==
 {{CC BY-4.0}}

2025-08-30T11:29:34Z

Initial chart.

New page

== Summary ==
Initial chart.
== Licensing ==
{{CC BY-4.0}}

← Older revision		Revision as of 04:51, 30 August 2025
Line 7:		Line 7:
	* [[Roquet2016 - Recombinase-based state machines\|Roquet FSM (2016)]]: 6-input FSM used 8 genes. Ran over 6 days [need to confirm]		* [[Roquet2016 - Recombinase-based state machines\|Roquet FSM (2016)]]: 6-input FSM used 8 genes. Ran over 6 days [need to confirm]
	* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours		* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours
			* Synthetic insulin - 2 peptides in E. coli. Batches run for 24-72 hours
	* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours		* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours
	* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours		* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours

← Older revision		Revision as of 04:43, 30 August 2025
Line 8:		Line 8:
	* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours		* [[Nielsen2016 - Genetic circuit design automation\|Cello logic gates (2016)]]: 11 genes in half-adder, ran for 4-8 hours
	* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours		* [[Yim2011 - Metabolic engineering of E. coli for production of 1,4-BDO\|Geno 1,4-BDO (2011)]]: 6 genes in E. coli. Batches run for 24-72 hours
	* [[~~Srinivasan~~ Srinivasan and Smolke: 26 genes (+ 8 deletions) in yeast for 72 hours		* [[Srinivasan2020 - Biosynthesis of medicinal tropane alkaloids in yeast\|Srinivasan and Smolke (2020)]]: 26 genes (+ 8 deletions) in yeast for 72 hours
	* [[http:en.wikipedia.org/wiki/Tardigrade\|Tardigrade]]: lives ~2 months, 11-14K genes		* [[http:en.wikipedia.org/wiki/Tardigrade\|Tardigrade]]: lives ~2 months, 11-14K genes
	* [[http:en.wikipedia.org/wiki/Carpenter_ant\|Carpenter ant]]: 17K genes, lives for a year, 2-6 weeks w/out food		* [[http:en.wikipedia.org/wiki/Carpenter_ant\|Carpenter ant]]: 17K genes, lives for a year, 2-6 weeks w/out food